2018 Original Papers / 2018 原著論文
- Kutsumura, N.; Kiriseko, A.; Niwa, K.; Saito, T.
“Total Syntheses of 3-epi-Litsenolide D2 and Lincomolide A”
J. Org. Chem. 2018, 83, 11450-11457. (web) - Sugiyama, A.; Yamada, M.; Siatoh, A.; Nagase, H.; Oka, J.; Yamada, M.
“Administration of a delta opioid receptor agonist KNT-127 to the basolateral amygdala has robust anxiolytic-like effects in rats”
Psychopharmacol. 2018, 235, 2947-2955. (web) - Saitoh, A.; Soda, A.; Kayashima, S.; Yoshizawa, K.; Oka, J.; Nagase, H.; Yamada, M.
“A delta opioid receptor agonist, KNT-127, in the prelimbic medial prefrontal cortex attenuates glial glutamate transporter blocker-induced anxiety-like behavior in mice”
J. Pharmacol. Sci. 2018, 138, 176-183. (web) - Toyama, S.; Shimoyama, N.; Tagaito, Y.; Nagase, H.; Saitoh, T.; Yanagisawa, M.; Shimoyama, M.
“Nonpeptide Orexin-2 Receptor Agonist Attenuates Morphine-induced Sedative Effects in Rats”
Anesthesiology 2018, 128, 992-1003. (web) - Wang, Y.; Cao, L.; Lee, C.-Y.; Matsuo, T.; Wu, K.; Asher, G.; Tang, L.; Saitoh, T.; Russell, J.; Klewe-Nebenius, D.; Wang, L.; Soya, S.; Hasegawa, E.; Cherasse, Y.; Zhou, J.; Li, Y.; Wang, T.; Zhan, X.; Miyoshi, C.; Irukayama, Y.; Cao, J.; Meeks, J. P.; Gautron, L.; Wang, Z.; Sakurai, K.; Funato, H.; Sakurai, T.; Yanagisawa, M.; Nagase, H.; Kobayakawa, R.; Kobayakawa, K.; Beutler, B.; Liu, Q.
“Large-scale forward genetics screening identifies Trapa1 as a chemosensor for predator odor-evoked innate fear behaviors”
Nat. Commun. 2018, 9(2041). (web)
- Ohshita, R.; Kutsumura, N.; Nagumo, Y.; Yamamoto, N.; Saitoh, T.; Hirayama, S, Fujii, H.; Nagase, H.
“Synthesis of Novel 1,3-Dioxa-5-thiazatriquinane and 1-Oxa-3,5-dithiazatriquinane Derivatives and their Pharmacologies”
Heterocycles 2018, 97, 687-695. (web) (Invited Paper) - Kutsumura, N.; Koyama, Y.; Suzuki, Y.; Tominaga, K.; Yamamoto, N.; Saitoh, T.; Nagumo, Y.; Nagase, H.
“Favorskii-Type Rearrangement of the 4,5-Epoxymorphinan Skeleton”
Org. Lett. 2018, 20, 1559-1562. (web) - Ohrui, S.; Yamamoto, N.; Saitoh, T.; Kutsumura, N.; Nagumo, Y.; Irukayama-Tomobe, Y.; Ogawa, Y.; Ishikawa, Y.; Watanabe, Y.; Hayakawa, D.; Gouda, H.; Yanagisawa, M.; Nagase, H.
“Essential structure of orexin 1 receptor antagonist YNT-707, Part II: Drastic effect of the 14-hydroxy group on the orexin 1 receptor antagonistic activity”
Bioorg. Med. Chem. Lett. 2018, 28, 774-777. (web) - Saitoh, A.; Tominaga, H.; Ogawa, Y.; Irukayama-Tomobe, Y.; Yamada, M.; Yanagisawa, M.; Nagase, H.
“Effects of the delta opioid receptor agonist KNT-127 on electroencephalographic activity in mice”
Pharmacol. Rep. 2018, 70, 350-354. (web) - Tateno, K.; Ogawa, R.; Sakamoto, R.; Tsuchiya, M.; Kutsumura, N.; Otani, T.; Ono, K.; Kawai, H.; Saito, T.
“Dibenzopyrrolo[1,2-a][1,8]naphthyridines: Synthesis and Structural Modification of Fluorescent L-Shaped Heteroarenes”
J. Org. Chem. 2018, 83, 690-702. (web) - Kutsumura, N.; Okada, T.; Imaide, S.; Fujii, H.; Nagase, H.
“Acetic Anhydride-Mediated Retro-Ene Reaction via a [4.4.3]Propellane Skeleton Intermediate Containing a Quaternary Ammonium Linkage”
Synthesis 2018, 50, 4263-4269. (web) (Invited Paper) - Saitoh, A.; Suzuki, S.; Soda, A.; Ohashi, M.; Yamada, M.; Oka, J.; Nagase, H.; Yamada, M.
“The delta opioid receptor agonist KNT-127 in the prelimbic medial prefrontal cortex attenuates veratrine-induced anxiety-like behaviors in mice”
Behav. Brain Res. 2018, 336, 77-84. (web)