Sep. 9, 2023
The following presentation was made at the 53rd Annual Meeting of the Japanese Society of Neuropsychopharmacology.
■Subject: 新規創製選択的オレキシン1受容体作動薬の鎮痛効果と疼痛モデルマウスにおける治療有効性の解析
Kao Hashimoto, Yasuyuki Nagumo, Keita Iio,Taisei Hasegawa, Akihisa Tokuda, Hikari Yamamoto, Yasuo Uchida, Noriki Kutsumura, Masashi Yanagisawa, Tsuyoshi Saitoh, Hiroshi Nagase
May 20, 2023
“Unexpected Rearrangement Reactions of the 14-Aminonaltrexone Skeleton”
Maeda, K.; Ohrui, S.; Tokuda, A.; Nagumo, Y.; Yamamoto, N.; Tanimura, R.; Saitoh, T.; Kutsumura, N.; Nagase, H.
Org. Lett. 2023, 25, 3407-3411. (web)
Apr. 28, 2023
“Design and Synthesis of Orexin 1 Receptor-Selective Agonists”
Iio, K.; Hashimoto, K.; Nagumo, Y.; Amezawa, M.; Hasegawa, T.; Yamamoto, N.; Kutsumura, N.; Takeuchi, K.; Ishikawa, Y.; Yamamoto, H.; Tokuda, A.; Sato, T.; Uchida, Y.; Inoue, A.; Tanimura, R.; Yanagisawa, M.; Nagase, H.; Saitoh, T.
J. Med. Chem. 2023, 66, 5453-5464. (web)
Apr. 24, 2023
The following students received the Best Student Presentation Award at the 143rd Annual Meeting of the Pharmaceutical Society of Japan!
Tomoya Kakumoto (B4): Synthesis and evaluation of novel morphinan derivatives toward separation of adverse effects of δ opioid receptor agonists
Keita Kajino (D1): Design and synthesis of novel κ opioid receptor agonist without sedative effect
Kao Hashimoto (D1): Analysis of orexin 1 receptor-mediated pain control mechanisms
Apr. 3rd, 2023
Fiscal year 2023 has started.
